Quantification of disease activity in Crohn's disease by computer analysis of Tc-99m hexamethyl propylene amine oxime (HMPAO) labelled leucocyte images.
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منابع مشابه
Technetium-99m hexamethyl propylene amine oxime granulocyte scintigraphy in Crohn's disease: diagnostic and clinical relevance.
Scintigraphy with autologous granulocytes labelled by technetium-99m hexamethyl, propylene amine oxime (99mTc-HMPAO) was performed in 103 Crohn's disease patients and 52 healthy controls. In 31 patients endoscopic and histologic activity was compared with scan activity index. In the 98 patients with a positive scan, the extent of Crohn's disease, assessed by scintigraphy, was compared with that...
متن کامل99mTc-HMPAO leucocyte scintigraphy fails to detect Crohn's disease in the proximal gastrointestinal tract.
OBJECTIVE To investigate the use of (99m)Tc-HMPAO (hexamethyl propylene amine oxime) leucocyte scintigraphy as a non-invasive screening test for inflammatory bowel disease. PATIENTS 10 children with suspected Crohn's disease, in whom routine investigation using barium contrast radiology, upper gastrointestinal endoscopy, colonoscopy, and mucosal biopsies had identified severe gastroduodenal a...
متن کاملComparison of Tc-99m Ethylenedicysteine (Tc-99m EC) with Tc-99m DPTA in evaluation of renal disease [Persian]
Tc-99m-EC is a new renal radiopharmaceutical introduced as an alternative for Tc-99m MAG3. Twenty-three normal volunteers and patients in different .stages of renal disease were evaluated with Te-99m EC and Tc-99m DTPA. The mean initial uptake of EC was significantly higher as compared to DTPA. There was a high correlation between rectangular and hand-drawn ROls for kidney and background,...
متن کاملLabelled leucocyte scintigraphy in inflammatory bowel disease: clinical applications.
Labelled leucocyte imaging is an established technique for the detection of inflammation and sepsis. Of the many radioisotopes used to label leucocytes, Indiuml1 tropolonate (11 1In) and Technetium-99m hexamethyl propylene amine oxime (99mTc HMPAO) are the most widely used. Leucocytes are obtained from heparinised, peripheral venous blood (40-100 ml) and then separated from erythrocytes and pla...
متن کامل(99m)Tc hexamethyl-propylene-aminoxime single-photon emission computed tomography prediction of conversion from mild cognitive impairment to Alzheimer disease.
OBJECTIVE To examine the utility of single-photon emission computed tomography (SPECT) to predict conversion from mild cognitive impairment (MCI) to Alzheimer disease (AD). DESIGN Longitudinal, prospective study. SETTING University-based memory disorders clinic. PARTICIPANTS One hundred twenty seven patients with MCI and 59 healthy comparison subjects followed up for 1-9 years. MEASUREM...
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ژورنال
عنوان ژورنال: Gut
سال: 1993
ISSN: 0017-5749
DOI: 10.1136/gut.34.1.68